Human pluripotent stem cell process parameter optimization in a small scale suspension bioreactor
نویسندگان
چکیده
منابع مشابه
Human pluripotent stem cell process parameter optimization in a small scale suspension bioreactor
Background As cell-based therapies begin to enter clinical trials, human pluripotent stem cells (PSCs) present a reliable and robust source of cells for differentiation into all cell types in the human body [1]. PSC may one day provide cells for new treatment options for a wide range of diseases including cardiovascular disease, neurodegenerative diseases, and diabetes. The large numbers of cel...
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Successful isolation, derivation and culturing of human pluripotent stem cells, including human embryonic stem cells (hESCs) and human induced pluripotent stem (hiPSCs) cells in laboratory scale has opened new horizones for cell therapy applications such as tissue engineering and regenerative medicine. However, most of the cell therapy protocols using these unique cells require large number of ...
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Multiple sclerosis (MS) is an autoimmune disease which affects myelin in the central nervous system (CNS) and leads to serious disability. Currently available treatments for MS mainly suppress the immune system. Regenerative medicine-based approaches attempt to increase myelin repair by targeting endogenous progenitors or transplanting stem cells or their derivatives. Fingolimod exerts anti-inf...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2015
ISSN: 1753-6561
DOI: 10.1186/1753-6561-9-s9-o10